Interest of rabbit-induced pluripotent stem cells for the conservation of this species.

Interest of rabbit-induced pluripotent stem cells for the conservation of this species.

Interest of rabbit-induced pluripotent stem cells for the conservation of this species.

To maintain the biodiversity of a given species, it is essential to develop cryopreservation techniques to conserve the genetic resources of that species in the long term. This can be done by storing embryos, male or female gametes, or somatic tissues.

Embryo and semen collection and cryopreservation techniques are effective and commonly used in rabbits, but they are not applicable to all individuals. In order to increase the number of samples stored, it is therefore desirable to be able to freeze somatic tissues that can be easily collected in the field without prior preparation of the animal. The somatic cells thus preserved can then be reprogrammed into induced pluripotent stem cells (or iPSC) to produce chimeric animals. We will review the current state of research on rabbit iPSCs and their relevance to the conservation of this species.
Communication at the 16th Journées de la Recherche Cunicole, 24 and 25 November 2015, Le Mans-France
Authors: Y. Tapponnier,, T. Joly, S. Voisin, N. Daniel, V. Duranthon, M. Afanassieff.

Modification date : 05 October 2023 | Publication date : 01 October 2019 | Redactor : CRB-Anim